Tested Applications
| Positive WB detected in | COS-7 cells, mouse ovary tissue, rat ovary tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| KD/KO | See 1 publications below |
| WB | See 1 publications below |
Product Information
31581-1-AP targets MXRA8 in WB, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag33429 Product name: Recombinant human MXRA8 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 168-308 aa of BC017312 Sequence: DGEKEVLAVARGAPALLTCVNRGHVWTDRHVEEAQQVVHWDRQPPGVPHDRADRLLDLYASGERRAYGPLFLRDRVAVGADAFERGDFSLRIEPLEVADEGTYSCHLHHHYCGLHERRVFHLTVAEPHAEPPPRGSPGNGS Predict reactive species |
| Full Name | matrix-remodelling associated 8 |
| Calculated Molecular Weight | 49 kDa |
| Observed Molecular Weight | 70 kDa |
| GenBank Accession Number | BC017312 |
| Gene Symbol | MXRA8 |
| Gene ID (NCBI) | 54587 |
| RRID | AB_3742451 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q9BRK3 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
The MXRA8 protein (Matrix Remodeling Associated 8, also known as LIM domain protein aspirin or DRAGO) belongs to the MXRA (matrix remodeling associated) protein family. It is a type I transmembrane protein whose extracellular domain contains two immunoglobulin-like (Ig-like) domains. MXRA8 primarily serves as an entry receptor for various pathogenic alphaviruses (such as chikungunya virus and Ross River virus) by specifically binding to the E2/E1 glycoprotein complex on the viral envelope, thereby mediating viral attachment and membrane fusion.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for MXRA8 antibody 31581-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
