MYT1L Polyclonal antibody

• Featured Product
• KD/KO Validated

MYT1L Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

WB, IP, IF, ELISA

Conjugate

Unconjugated

Publications

5

Cat no : 25234-1-AP

Synonyms

KIAA1106, MyT1 L, MYT1L, NZF1

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Validation Data Gallery

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  WB analysis of HepG2 using 25234-1-AP

  HepG2 cells were subjected to SDS PAGE followed by western blot with 25234-1-AP (MYT1L Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

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  WB analysis of HeLa using 25234-1-AP

  HeLa cells were subjected to SDS PAGE followed by western blot with 25234-1-AP (MYT1L Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: HepG2 cells, HeLa cells

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• KD/KO: See 1 publications below
• WB: See 3 publications below
• IF: See 2 publications below
• IP: See 2 publications below

Product Information

25234-1-AP targets MYT1L in WB, IP, IF, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Cited Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: MYT1L fusion protein Ag18698
• Full Name: myelin transcription factor 1-like
• Calculated Molecular Weight: 1186 aa, 133 kDa
• Observed Molecular Weight: 110 kDa
• GenBank Accession Number: BC137273
• Gene Symbol: MYT1L
• Gene ID (NCBI): 23040
• RRID: AB_2879978
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Publications

Species	Application	Title
mouse	WB,IF	Neuron; A MYT1L syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation.; Authors - Jiayang Chen
human	WB	Brain Res Bull; miRNA-338-3p inhibits glioma cell proliferation and progression by targeting MYT1L; Authors - Zhengtao Yu ; KD Validated
human	IF	Nat Neurosci; Age-related Huntington's disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy; Authors - Young Mi Oh
mouse	IP	Genome Res; MYT1L is required for suppressing earlier neuronal development programs in the adult mouse brain; Authors - Jiayang Chen
human	WB,IP	bioRxiv; Asynchronous microexon splicing of LSD1 and PHF21A during neurodevelopment; Authors - Masayoshi Nagai