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  • KD/KO Validated

Malectin Polyclonal antibody

Malectin Polyclonal Antibody for WB, ELISA
Cat No. 26655-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF, ELISA

MLEC, KIAA0152

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Tested Applications

Positive WB detected inmouse colon tissue, human placenta tissue, rat colon tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

26655-1-AP targets Malectin in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag24379

Product name: Recombinant human MLEC protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 106-269 aa of BC000371

Sequence: EETFGYEVPIKEEGDYVLVLKFAEVYFAQSQQKVFDVRLNGHVVVKDLDIFDRVGHSTAHDEIIPMSIRKGKLSVQGEVSTFTGKLYIEFVKGYYDNPKVCALYIMAGTVDDVPKLQPHPGLEKKEEEEEEEEYDEGSNLKKQTNKNRVQSGPRTPNPYASDNS

Predict reactive species
Full Name malectin
Calculated Molecular Weight 292 aa, 32 kDa
Observed Molecular Weight 32 kDa
GenBank Accession NumberBC000371
Gene Symbol Malectin
Gene ID (NCBI) 9761
RRIDAB_2880591
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDQ14165
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Malectin is a conserved, endoplasmic reticulum (ER)-resident lectin that recognizes high mannose oligosaccharides displaying terminal glucose residues. Like other intracellular lectins involved in glycoprotein quality control, malectin is highly conserved in animals (PMID: 21298103).

Protocols

Product Specific Protocols
WB protocol for Malectin antibody 26655-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
ratWB

J Cell Biol

Competition for calnexin binding regulates secretion and turnover of misfolded GPI-anchored proteins

Authors - Amber M Cheatham
humanWB

Exp Cell Res

Blood coagulation factor VIII D1241E polymorphism leads to a weak malectin interaction and reduction of factor VIII posttranslational modification and secretion.

Authors - Ning Jiang
  • KD Validated

Mol Biol Cell

The prolyl isomerase FKBP11 is a secretory translocon accessory factor

Authors - Amanda DiGuilio
humanWB

Biochemistry

Integrated Structural Analysis of N-Glycans and Free Oligosaccharides Allows for a Quantitative Evaluation of ER Stress.

Authors - Naoki Fujitani
mouseWB,IF

Nat Commun

The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes

Authors - Shuangcheng Alivia Wu
humanWB,IF

Int Immunopharmacol

Identification of TAP1 as a T-cell related therapeutic target in gastric cancer by mediating oxalipliatin-related synergistic enhancement of immunotherapy

Authors - Yupeng Zhao
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