Anti-Human N-cadherin/CD325 Rabbit Recombinant Antibody

N-cadherin/CD325 Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

Human and More (1)

Applications

WB, FC

Conjugate

Unconjugated

Publications

1

CloneNo.

230259D7

Cat no : 98006-1-RR

Synonyms

Cadherin 2, CD325, CDH2, CDHN, CDw325, N cadherin, NCAD, Neural cadherin

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Validation Data Gallery

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  FC experiment of HeLa using 98006-1-RR

  1x10^6 HeLa cells were stained with 0.25 ug Anti-Human N-cadherin (98006-1-RR, Clone: 230259D7) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (red), or 0.25 ug Control Antibody and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (blue). Cells were not fixed.

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Tested Applications

• Positive FC detected in: HeLa cells

Recommended dilution

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

• WB: See 1 publications below

Product Information

98006-1-RR targets N-cadherin/CD325 in WB, FC applications and shows reactivity with Human samples.

• Tested Reactivity: Human
• Cited Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant protein
• Full Name: cadherin 2, type 1, N-cadherin (neuronal)
• Calculated Molecular Weight: 100 kDa
• GenBank Accession Number: NM_001792.4
• Gene Symbol: CDH2
• Gene ID (NCBI): 1000
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS with 0.09% sodium azide.
• Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Background Information

Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. N-cadherin (neural cadherin), also known as CDH2 (cadherin 2), is a 130-kDa transmembrane protein and a classical member of the cadherin superfamily which also include E-, P-, R-, and B-cadherins. Expression of N-cadherin has been reported on various cell types including neurons, endothelial cells and cardiac myocytes (PMID: 11282032; 9508779; 8125202). N-cadherin has functions in early brain morphogenesis, synaptogenesis and synaptic plasticity (PMID: 23321619).

Publications

Species	Application	Title
human	WB	Cell Oncol (Dordr); Dexmedetomidine promotes colorectal cancer progression via Piwil2 signaling; Authors - Jing Dong