NAIP Polyclonal antibody

NAIP Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 55153-1-AP

Synonyms

BIRC1, NAIP, NLRB1, psiNAIP

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Validation Data Gallery

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  WB analysis using 55153-1-AP

  HeLa cells were subjected to SDS PAGE followed by western blot with 55153-1-AP (NAIP antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: HeLa cells, HepG2 cells

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

55153-1-AP targets NAIP in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Peptide
• Full Name: NLR family, apoptosis inhibitory protein
• Calculated Molecular Weight: 160 kDa
• Observed Molecular Weight: 160 kDa
• GenBank Accession Number: NM_004536
• Gene Symbol: NAIP
• Gene ID (NCBI): 4671
• RRID: AB_2881277
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

NAIP, also named as BIRC1, prevents motor-neuron apoptosis induced by a variety of signals. It is a possible role in the prevention of spinal muscular atrophy that seems to be caused by inappropriate persistence of motor-neuron apoptosis: mutated or deleted forms of NAIP have been found in individuals with severe spinal muscular atrophy. (PMID: 7813013; PMID: 8552191). This antibody is specal to NAIP.