HEM1; NCKAP1L Polyclonal antibody
HEM1; NCKAP1L Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
ELISA
Conjugate
Unconjugated
Cat no : 10454-1-AP
Synonyms
Validation Data Gallery
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
10454-1-AP targets HEM1; NCKAP1L in ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | HEM1; NCKAP1L fusion protein Ag0706 |
Full Name | NCK-associated protein 1-like |
Calculated Molecular Weight | 128 kDa |
GenBank Accession Number | BC001604 |
Gene Symbol | NCKAP1L |
Gene ID (NCBI) | 3071 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
Membrane-associated protein HEM1 encoded by human NCKAP1L (Nck-associated protein 1-like) gene belongs to the HEM family of tissue-specific transmembrane proteins which are highly conserved from invertebrates through mammals. HEM1 is characterized as hematopoietic cell-specific actin regulatory protein. HEM1 is a component of the "WAVE" complex, which signals downstream of activated Rac to stimulate F-actin polymerization in response to immuno-receptor signaling. Therefore, HEM1 may be essential for most active processes dependent on reorganization of the actin cytoskeleton in immune cells.