Product Information
29936-1-PBS targets NETO1 in IHC, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag32177 Product name: Recombinant human NETO1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 23-213 aa of NM_138999 Sequence: TKKGTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSK Predict reactive species |
| Full Name | neuropilin (NRP) and tolloid (TLL)-like 1 |
| Calculated Molecular Weight | 60 kDa |
| GenBank Accession Number | NM_138999 |
| Gene Symbol | NETO1 |
| Gene ID (NCBI) | 81832 |
| RRID | AB_3742322 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8TDF5 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
The NETO1 protein (neuropilin and tolloid-like protein 1) is a member of the NETO family. It is a type I transmembrane protein primarily expressed in the central nervous system. Serving as an important auxiliary subunit of glutamate receptors (especially kainate receptors and NMDA receptors), NETO1 plays a critical role in synaptic plasticity, learning, and memory by regulating receptor trafficking, gating properties, and synaptic localization. Its abnormalities are associated with neuropsychiatric disorders such as schizophrenia and epilepsy.
