NEUROD4 Polyclonal antibody

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• NEUROD4 Polyclonal antibody (14610-1-AP)

NEUROD4 Polyclonal Antibody for WB, ELISA

Cat No. 14610-1-AP Copied!

Publications (2)

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Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF, ELISA

Synonyms

ATH 3, ATH3, ATH-3, Atoh3, bHLHa4

• 

  WB analysis of Y79 using 14610-1-AP

  Y79 cells were subjected to SDS PAGE followed by western blot with 14610-1-AP (NEUROD4 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  WB analysis of Neuro-2a using 14610-1-AP

  Neuro-2a cells were subjected to SDS PAGE followed by western blot with 14610-1-AP (NEUROD4 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  WB analysis of Y79 using 14610-1-AP

  Y79 cells were subjected to SDS PAGE followed by western blot with 14610-1-AP (NEUROD4 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Tested Applications

• Positive WB detected in: Y79 cells, Neuro-2a cells

Recommended dilution

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

14610-1-AP targets NEUROD4 in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Cited Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag6183

  Product name: Recombinant human NEUROD4 protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 1-255 aa of BC040961

  Sequence: MTKARLERFRARRVKANARERTRMHGLNDALDNLRRVMPCYSKTQKLSKIETLRLARNYIWALSEVLETGQTPEGKGFVEMLCKGLSQPTSNLVAGCLQLGPQSVLLEKHEDKSPICDSAISVHNFNYQSPGLPSPPYGHMETHLLHLKPQVFKSLGESSFGSHLPDCSTPPYEGPLTPPLSISGNFSLKQDGSPDLEKSYSFMPHYPSSSLSSGHVHSTPFQAGTPRYDVPIDMSYDSYPHHGIGTQLNTVFTE

• Full Name: neurogenic differentiation 4
• Calculated Molecular Weight: 37 kDa
• Observed Molecular Weight: 50-55 kDa
• GenBank Accession Number: BC040961
• Gene Symbol: NEUROD4
• Gene ID (NCBI): 58158
• RRID: AB_2878069
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9HD90
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

NEUROD4 is a basic helix-loop-helix (bHLH) transcription factor encoded by the NEUROD4 gene on human chromosome 12q13.2. It mediates neuronal differentiation and is required for amacrine cell fate specification in the retina. Expression is enriched in brain, adrenal gland, and retina. Orthologs exist in mouse (Math3), rat, zebrafish, and chick.

Publications

What published studies show

The NEUROD4 Polyclonal antibody (Cat# 14610-1-AP) has 2 total citations. These appear in Nature Neuroscience (2025) and Nature Communications (2016). The cited research fields include Alzheimer's disease and spinal cord Tau pathology, as well as oligodendrocyte myelination and VCAM1/CD69 signaling in the nervous system.

Automatically generated from the 2 publication citations by Able AI.

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
mouse	IF	Nat Neurosci; Spinal cord Tau pathology induces tactile deficits and cognitive impairment in Alzheimer's disease via dysregulation of CCK neurons; Authors - Yang Zhou
		Nat Commun; VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination.; Authors - Yuki Miyamoto