Validation Data Gallery
|Positive WB detected in||mouse brain tissue, rat brain tissue|
|Positive IP detected in||mouse brain tissue|
|Positive IHC detected in||mouse brain tissue, human spleen tissue, human prostate hyperplasia tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Positive FC detected in||SH-SY5Y cells|
|Western Blot (WB)||WB : 1:500-1:2000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB|
|Immunohistochemistry (IHC)||IHC : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
55014-1-AP targets p75NTR in WB, IP, IHC, FC, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse, rat|
|Host / Isotype||Rabbit / IgG|
|Full Name||nerve growth factor receptor (TNFR superfamily, member 16)|
|Calculated molecular weight||45 kDa|
|Observed molecular weight||70-75 kDa|
|GenBank accession number||NM_002507|
|Gene ID (NCBI)||4804|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
NGFR, also named as TNFRSF16, Gp80-LNGFR, p75 ICD and CD271, is a low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. It mediates cell survival as well as cell death of neural cells. The antibody is specific to NGFR.
J Exp Med
CXCR4 regulates Plasmodium development in mouse and human hepatocytes.
Int J Mol Sci
Direct Enhancement Effect of Hippocampal Cholinergic Neurostimulating Peptide on Cholinergic Activity in the Hippocampus
Int J Mol Sci
Early Clinical Outcomes of the First Commercialized Human Autologous Ex Vivo Cultivated Oral Mucosal Epithelial Cell Transplantation for Limbal Stem Cell Deficiency: Two Case Reports and Literature Review
LMO1 Plays an Oncogenic Role in Human Glioma Associated With NF-kB Pathway.
Stem Cell Res Ther
NT3P75-2 gene-modified bone mesenchymal stem cells improve neurological function recovery in mouse TBI model.
J Mol Med (Berl)
MESP2 variants contribute to conotruncal heart defects by inhibiting cardiac neural crest cell proliferation.
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
Renato (Verified Customer) (02-27-2019)
Produces 3 perfectly discerning bands, but one of which clearly identifiable as p75NTR as it shows at the expected molecular weight. Used as diluent 5% BSA.