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NGFR/TNFRSF16 Recombinant monoclonal antibody, PBS Only (86920-2-PBS)

NGFR/TNFRSF16 Recombinant monoclonal antibody, PBS Only

Name: NGFR/TNFRSF16 Recombinant monoclonal antibody, PBS Only, 100ug
Brand: Proteintech
SKU: 86920-2-PBS-100UG

NGFR/TNFRSF16 Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 86920-2-PBS

Clone No.251010A6

Review Product

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

NGFR, CD271, Gp80 LNGFR, Gp80-LNGFR, Low-affinity nerve growth factor receptor

Formulation: PBS Only

PBS, Azide, Glycerol

PBS Only

Conjugate: Unconjugated

Size/Concentration:

SKU:

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Freight/Packing: -

Quantity

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WB analysis using 86920-2-RR (same clone as 86920-2-PBS)
Various lysates were subjected to SDS PAGE followed by western blot with 86920-2-RR (NGFR/TNFRSF16 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86920-2-PBS in a different storage buffer formulation.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
WB analysis using 86920-2-RR (same clone as 86920-2-PBS)
Various lysates were subjected to SDS PAGE followed by western blot with 86920-2-RR (NGFR/TNFRSF16 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86920-2-PBS in a different storage buffer formulation.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
Affinity and Kinetic Characterization of 86920-2-RR
Biolayer interferometry (BLl) kinetic assays of 86920-2-RR against Human NGFR/TNFRSF16 were performed. The affinity constant is 1.46 nM.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

Overview

Tested Applications
Product Information

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MSDS SDS

Product Information

86920-2-PBS targets NGFR/TNFRSF16 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity	human
Host / Isotype	Rabbit / IgG
Class	Recombinant
Type	Antibody
Immunogen	CatNo: Eg4829 Product name: Recombinant Human NGFR/TNFRSF16 protein (rFc Tag)(HPLC verified) Source: mammalian cells-derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 29-250 aa of NM_002507.4 Sequence: KEACPTGLYTHSGECCKACNLGEGVAQPCGANQTVCEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSAPCVEADDAVCRCAYGYYQDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVCEDTERQLRECTRWADAECEEIPGRWITRSTPPEGSDSTAPSTQEPEAPPEQDLIASTVAGVVTTVMGSSQPVVTRGTTDN Predict reactive species
Full Name	nerve growth factor receptor (TNFR superfamily, member 16)
Calculated Molecular Weight	45 kDa
Observed Molecular Weight	70-75 kDa
GenBank Accession Number	NM_002507.4
Gene Symbol	p75NTR
Gene ID (NCBI)	4804
RRID	AB_3745205
Conjugate	Unconjugated
Form	Liquid
Purification Method	Protein A purification
UNIPROT ID	P08138-1
Storage Buffer	PBS only, pH 7.3.
Storage Conditions	Store at -80°C.

Background Information

p75NTR, also named TNFRSF16, Gp80-LNGFR, p75 ICD, and CD271, is a low-affinity receptor that can bind to NGF, BDNF, NT-3, and NT-4. It mediates cell survival as well as cell death of neural cells. The antibody is specific to NGFR.