Anti-Mouse NGFR/TNFRSF16 Rabbit Recombinant Antibody, PBS Only

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  FC experiment of Transfected HEK-293T using 98391-2-RR (same clone as 98391-2-PBS)

  1x10^6 HEK-293T cells or Ngfr transfected HEK-293T cells were stained with 0.25 ug Anti-Mouse NGFR/TNFRSF16 Rabbit RecAb (98391-2-RR, Clone:242634B10) and PE-Conjugated Goat Anti-Rabbit IgG(H+L).Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer. This data was developed using the same antibody clone with 98391-2-PBS in a different storage buffer formulation.

• 

  FC experiment of Transfected HEK-293T using 98391-2-RR (same clone as 98391-2-PBS)

  1x10^6 HEK-293T cells(left) or Ngfr transfected HEK-293T cells(right) were stained with 0.25 ug Anti-Mouse NGFR/TNFRSF16 Rabbit RecAb (98391-2-RR, Clone:242634B10) (red), or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L).Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer. This data was developed using the same antibody clone with 98391-2-PBS in a different storage buffer formulation.

NGFR/TNFRSF16 Uni-rAb^® Recombinant Antibody for FC

Cat No. 98391-2-PBS

Clone No.242634B10

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

FC

Synonyms

CD271, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, Low-affinity nerve growth factor receptor p75NGFR, Low-affinity nerve growth factor receptor p75NGR

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Product Information

98391-2-PBS targets NGFR/TNFRSF16 in FC applications and shows reactivity with mouse samples.

• Tested Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Eg2651

  Product name: Recombinant mouse Ngfr protein (C-rFc)

  Source: mammalian cells-derived, V37

  Tag: C-rFc

  Domain: 32-252 aa of NM_033217.3

  Sequence: KETCSTGMYTHSGECCKACNLGEGVAQPCGANQTVCEPCLDSVTFSDVVSATEPCKPCTECLGLQSMSAPCVEADDAVCRCSYGYYQDEETGRCEACSVCGVGSGLVFSCQDKQNTVCEECPEGTYSDEANHVDPCLPCTVCEDTERQLRECTPWADAECEEIPGRWITRSTPPEGSDVTTPSTQEPEAPPERDLIASTVADTVTTVMGSSQPVVTRGTAD

• Full Name: nerve growth factor receptor (TNFR superfamily, member 16)
• Calculated Molecular Weight: 46 kDa
• GenBank Accession Number: NM_033217.3
• Gene Symbol: Ngfr
• Gene ID (NCBI): 18053
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q9Z0W1-1
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

The nerve growth factor (NGF) receptor (NGFR), also known as p75NTR, TNFRSF16, belongs to the tumor necrosis factor receptor superfamily, which is a low-affinity receptor of neurotrophins including NGF,1 brain-derived neurotrophic factor (BDNF),2 and neurotrophin-3, -4, and -5.It is now apparent that expression of NGFR is ubiquitous and not limited to the nervous system, being expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells and myoepithelial cells (PMID: 38307025, 16424897).