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NKAPL Polyclonal antibody

NKAPL Polyclonal Antibody for WB, ELISA

Cat No. 26993-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

C6orf194, NFKB activating protein like, NKAP like protein

Formulation:  PBS, Azide, Glycerol
PBS, Azide, Glycerol
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Tested Applications

Positive WB detected inmouse testis tissue, NTERA-2 cl.D1 cells, rat testis tissue, PC-3 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

26993-1-AP targets NKAPL in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag25779

Product name: Recombinant human NKAPL protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 201-275 aa of BC101685

Sequence: YSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEEDLSEATWMEQPNVADTM

Predict reactive species
Full Name NFKB activating protein-like
Observed Molecular Weight52 kDa, 65 kDa
GenBank Accession NumberBC101685
Gene Symbol NKAPL
Gene ID (NCBI) 222698
RRIDAB_3742208
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDQ5M9Q1
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

NKAPL (NF-kappa-B activating protein-like), also known as C6orf194, is a nuclear protein-coding gene located on chromosome 6p22.1. Initially identified as a germ cell-specific suppressor of Notch signaling essential for spermatogenesis, NKAPL has recently emerged as a tumor suppressor in non-small cell lung cancer through TRIM21 stabilization and NF-κB pathway inhibition. Additionally, NKAPL promoter methylation serves as a prognostic biomarker in multiple malignancies.(PMID: 25875095; 40605974)

Protocols

Product Specific Protocols
WB protocol for NKAPL antibody 26993-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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