Product Information
84355-1-PBS targets NKX6-1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | Peptide Predict reactive species |
Full Name | NK6 homeobox 1 |
Calculated Molecular Weight | 38 kDa |
Observed Molecular Weight | 45-52 kDa |
GenBank Accession Number | NM_006168 |
Gene Symbol | NKX6-1 |
Gene ID (NCBI) | 4825 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | P78426 |
Storage Buffer | PBS only, pH 7.3. |
Storage Conditions | Store at -80°C. |
Background Information
NK6 homeobox 1 (NKX6-1) is a potent bifunctional transcription regulator that binds to AT-rich DNA sequences within the promoter region of target genes. NKX6-1 belongs to the class II proteins of neuronal progenitor factors, and the function of it is to enhance proliferation, glucose-stimulated insulin secretion, and survival in mature pancreatic beta-cells, and it is also essential in regional patterning and neuronal fate determination in central nervous system.