NLRP1 Polyclonal antibody

NLRP1 Polyclonal Antibody for IHC,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, IF,ELISA

Conjugate

Unconjugated

Cat no : 12256-1-AP

Synonyms

CARD7, CLR17.1, DEFCAP, DEFCAP L/S, KIAA0926, NAC, NALP1, NLRP1, PP1044, SLEV1, VAMAS1



Tested Applications

Positive IHC detected inmouse brain tissue, human pancreas cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

12256-1-AP targets NLRP1 in WB, IHC, IF,ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen NLRP1 fusion protein Ag2908
Full Name NLR family, pyrin domain containing 1
Calculated molecular weight 155 kDa
GenBank accession numberBC016965
Gene symbol NLRP1
Gene ID (NCBI) 22861
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Protocols

Product Specific Protocols
IHC protocol for NLRP1 antibody 12256-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Inflammation

Aspergillus fumigatus-Stimulated Human Corneal Epithelial Cells Induce Pyroptosis of THP-1 Macrophages by Secreting TSLP.

Authors - Qingshan Ji
humanWB,IF

Neuroscience

Overexpression of MicroRNA-9a-5p Ameliorates NLRP1 Inflammasome-mediated Ischemic Injury in Rats Following Ischemic Stroke.

Authors - Cao Yuze
humanIHC

Front Microbiol

Porphyromonas gingivalis-Induced NLRP3 Inflammasome Activation and Its Downstream Interleukin-1β Release Depend on Caspase-4.

Authors - Pei-Hui Ding
humanWB,IHC

Front Immunol

Cytokine Secretion and Pyroptosis of Thyroid Follicular Cells Mediated by Enhanced NLRP3, NLRP1, NLRC4, and AIM2 Inflammasomes Are Associated With Autoimmune Thyroiditis.

Authors - Qingling Guo
humanIF

Mol Neurodegener

The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease.

Authors - Marina Saresella
humanWB

MBio

Inducible Nitric Oxide Synthase Is a Key Host Factor for Toxoplasma GRA15-Dependent Disruption of the Gamma Interferon-Induced Antiparasitic Human Response.

Authors - Hironori Bando

Reviews

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


FH

Debanjan (Verified Customer) (08-17-2020)

The band was very clear and of exact molecular weight

  • Applications: Western Blot
  • Primary Antibody Dilution: 1:250
  • Cell Tissue Type: Human fibroblasts