NMNAT2 Recombinant monoclonal antibody, PBS Only

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  WB analysis using 84307-5-RR (same clone as 84307-5-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84307-5-RR (NMNAT2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84307-5-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84307-5-RR

  Biolayer interferometry (BLl) kinetic assays of 84307-5-RR against Human NMNAT2 were performed. The affinity constant is below 1 pM.

NMNAT2 Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 84307-5-PBS

Clone No.241484E10

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2, NaMN adenylyltransferase 2, KIAA0479, EC:2.7.7.1, C1orf15

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Product Information

84307-5-PBS targets NMNAT2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Ag26909

  Product name: Recombinant human NMNAT2 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 90-302 aa of BC020998

  Sequence: TCSVLEHHRDLMKRVTGCILSNVNTPSMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVDENANLGTVMRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRIMNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQLYINASG

• Full Name: nicotinamide nucleotide adenylyltransferase 2
• Calculated Molecular Weight: 34 kDa
• Observed Molecular Weight: 32-34 kDa
• GenBank Accession Number: BC020998
• Gene Symbol: NMNAT2
• Gene ID (NCBI): 23057
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: Q9BZQ4
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

NMNA2 (Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 ) is an axon survival factor required for the maintenance of healthy axons, it acts by delaying Wallerian axon degeneration which is an evolutionarily conserved process that drives the loss of damaged axons.