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  • KD/KO Validated

NPTX1 Polyclonal antibody

NPTX1 Polyclonal Antibody for IF, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF, CoIP, ELISA

Conjugate

Unconjugated

Cat no : 20656-1-AP

Synonyms

Neuronal pentraxin 1, neuronal pentraxin I, NPTX1



Tested Applications

Positive WB detected inHepG2 cells, mouse liver tissue
Positive IF detected inHela cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunofluorescence (IF)IF : 1:10-1:100
Sample-dependent, check data in validation data gallery

Product Information

20656-1-AP targets NPTX1 in WB, IF, CoIP, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name neuronal pentraxin I
Calculated molecular weight 47 kDa
Observed molecular weight 47 kDa
GenBank accession numberNM_002522
Gene symbol NPTX1
Gene ID (NCBI) 4884
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

NPTX1, also named as NP1, may mediate uptake of degraded synaptic material which could play an important role in synaptic remodeling. NPTX1 can mediate the neuronal and glial uptake of the snake venom toxin taipoxin. The antibody is specific to NPTX1.

Protocols

Product Specific Protocols
WB protocol for NPTX1 antibody 20656-1-APDownload protocol
IF protocol for NPTX1 antibody 20656-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Cancer Manag Res

NPTX1 promotes metastasis via integrin/FAK signaling in gastric cancer.

Authors - Hongfei Yan
  • KD Validated
WB

Acta Biochim Biophys Sin (Shanghai)

miR-139-5p mediates the palmitate-induced inhibition of insulin secretion by targeting neuronal pentraxin 1 in INS-1 cells.

Authors - Kai Zhang
mouseIF

PLoS One

RNA-seq analysis of gene expression profiles in isolated stria vascularis from wild-type and Alport mice reveals key pathways underling Alport strial pathogenesis.

Authors - Brianna Dufek
mouseWB, CoIP

Front Immunol

Identification of Neuronal Pentraxins as Synaptic Binding Partners of C1q and the Involvement of NP1 in Synaptic Pruning in Adult Mice.

Authors - Réka Á Kovács