Product Information
14019-1-AP targets NR2C2AP in ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | NR2C2AP fusion protein Ag5133 Predict reactive species |
| Full Name | nuclear receptor 2C2-associated protein |
| Calculated Molecular Weight | 16 kDa |
| GenBank Accession Number | BC057837 |
| Gene Symbol | NR2C2AP |
| Gene ID (NCBI) | 126382 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q86WQ0 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
NR2C2AP, also named as NR2C2, TRA16, PGR, PSBPC1, NR3C1, AR and OXT, belongs to the NR2C2AP family. It may act as a repressor of NR2C2-mediated transactivation by suppressing the binding between NR2C2/TR4 and the TR4-response element in target genes. NR2C2AP is mainly localized in the nucleus of cells as a repressor to suppress TR4-mediated transactivation. It can also block the interaction between TR4 and TR4 ligand-binding domain through interacting with TR4-DNA-binding and ligand-binding domains. It may function as a novel repressor to selectively suppress the TR4-mediated transactivation.
