NRG2 Polyclonal antibody, PBS Only

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• NRG2 Polyclonal antibody, PBS Only (20690-1-PBS)

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  WB analysis using 20690-1-AP (same clone as 20690-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 20690-1-AP (NRG2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20690-1-PBS in a different storage buffer formulation.

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  IHC staining of human gliomas using 20690-1-AP (same clone as 20690-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using 20690-1-AP (NRG2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20690-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human gliomas using 20690-1-AP (same clone as 20690-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using 20690-1-AP (NRG2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20690-1-PBS in a different storage buffer formulation.

NRG2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 20690-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Synonyms

neuregulin 2, neuregulin2, Neuregulin-2, NTAK, Pro NRG2

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Product Information

20690-1-PBS targets NRG2 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: neuregulin 2
• Calculated Molecular Weight: 92 kDa
• Observed Molecular Weight: 46 kDa
• GenBank Accession Number: NM_004883
• Gene Symbol: NRG2
• Gene ID (NCBI): 9542
• RRID: AB_3085611
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: O14511
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

NRG2 is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease.