NTB-A/SLAMF6 Recombinant monoclonal antibody, PBS Only

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  WB analysis using 84211-4-RR (same clone as 84211-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84211-4-RR (NTB-A/SLAMF6 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84211-4-PBS in a different storage buffer formulation.

• 

  IF Staining of Ramos using 84211-4-RR (same clone as 84211-4-PBS)

  Immunofluorescent analysis of (4% PFA) fixed Ramos cells using NTB-A/SLAMF6 antibody (84211-4-RR, Clone: 241384G5 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84211-4-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 84211-4-RR

  Biolayer interferometry (BLl) kinetic assays of 84211-4-RR against Human NTB-A/SLAMF6 were performed. The affinity constant is 2.73 nM.

NTB-A/SLAMF6 Uni-rAb^® Recombinant Antibody for WB, IF/ICC, Indirect ELISA

Cat No. 84211-4-PBS

Clone No.241384G5

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IF/ICC, Indirect ELISA

Synonyms

SLAMF6, Ly108, KALIb, KALI, CD352

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Product Information

84211-4-PBS targets NTB-A/SLAMF6 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Fusion Protein

• Full Name: SLAM family member 6
• Calculated Molecular Weight: 37kDa
• Observed Molecular Weight: 60 kDa
• GenBank Accession Number: NM_001184714.2
• Gene Symbol: SLAMF6
• Gene ID (NCBI): 114836
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: Q96DU3-1
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Signaling lymphocyte activation molecule 6 (SLAMF6) (Ly108 in mice, NTB-A or SF2000 in humans) is a homophilic receptor belonging to the superfamily immunoglobulin (Ig) domain-containing molecules (PMID:31199820). SLAMF6 is a type I transmembrane protein with two extracellular immunoglobins (Ig)-like domains and three cytoplasmic tyrosine-based signaling motifs, one of which is immunoreceptor tyrosine-based switch motif (PMID:31315913). SLAMF6 is expressed on a wide variety of immune cells including T cells (also TFH), B cells, NK cells (expressed in humans only), double positive thymocytes, eosinophils, and neutrophils (mouse only) (PMID:11862385).