TrkC Monoclonal antibody

• 

  WB analysis using 66380-1-Ig

  Various lysates were subjected to SDS PAGE followed by western blot with 66380-1-Ig (TrkC antibody at dilution of 1:3000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of fetal human brain using 66380-1-Ig

  fetal human brain tissue were subjected to SDS PAGE followed by western blot with 66380-1-Ig (TrkC antibody at dilution of 1:3000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of SH-SY5Y using 66380-1-Ig

  SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 66380-1-Ig (TrkC antibody at dilution of 1:3000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of PC-12 using 66380-1-Ig

  PC-12 cells were subjected to SDS PAGE followed by western blot with 66380-1-Ig (TrkC antibody at dilution of 1:3000 incubated at room temperature for 1.5 hours.

TrkC Monoclonal Antibody for WB, ELISA

Cat No. 66380-1-Ig

Clone No.2A7F11

Publications(1)

Reviews (1)

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat, pig

Applications

WB, IF, ELISA

Synonyms

NTRK3, 2A7F11, EC:2.7.10.1, GP145 TrkC, gp145(trkC)

---

Tested Applications

• Positive WB detected in: pig brain tissue, SH-SY5Y cells, PC-12 cells, fetal human brain tissue, rat brain tissue, mouse brain tissue

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:6000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• WB: See 1 publications below
• IF: See 1 publications below

Product Information

66380-1-Ig targets TrkC in WB, IF, ELISA applications and shows reactivity with human, mouse, rat, pig samples.

• Tested Reactivity: human, mouse, rat, pig
• Cited Reactivity: human
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag2635

  Product name: Recombinant human NTRK3 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 36-350 aa of BC013693

  Sequence: CVCSKTEINCRRPDDGNLFPLLEGQDSGNSNGNASINITDISRNITSIHIENWRSLHTLNAVDMELYTGLQKLTIKNSGLRSIQPRAFAKNPHLRYINLSSNRLTTLSWQLFQTLSLRELQLEQNFFNCSCDIRWMQLWQEQGEAKLNSQNLYCINADGSQLPLFRMNISQCDLPEISVSHVNLTVREGDNAVITCNGSGSPLPDVDWIVTGLQSINTHQTNLNWTNVHAINLTLVNVTSEDNGFTLTCIAENVVGMSNASVALTVYYPPRVVSLEEPELRLEHCIEFVVRGNPPPTLHWLHNGQPLRESKIIHV

• Full Name: neurotrophic tyrosine kinase, receptor, type 3
• Calculated Molecular Weight: 839 aa, 94 kDa
• Observed Molecular Weight: 110 kDa, 160 kDa
• GenBank Accession Number: BC013693
• Gene Symbol: TrkC
• Gene ID (NCBI): 4916
• RRID: AB_2881756
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein G purification
• UNIPROT ID: Q16288
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

TrkC (Tropomyosin Receptor Kinase C), also known as NTRK3 (Neurotrophic Tyrosine Kinase Receptor Type 3), belongs to the Trk family of receptor tyrosine kinases, which also includes TrkA and TrkB. These receptors are primarily involved in the development and function of the nervous system.

Publications

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
human	WB,IF	Bioact Mater; Construction of functional neural network tissue combining CBD-NT3-modified linear-ordered collagen scaffold and TrkC-modified iPSC-derived neural stem cells for spinal cord injury repair; Authors - Zhaoping Wu

Reviews

The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.

---

FH

Reyes (Verified Customer) (09-24-2025)

NTRK3 or TRKC (in green) marked mainly a specific subtype of astrogliosis in FCD human tissue

• Applications: Immunofluorescence
• Primary Antibody Dilution: 1:100
• Cell Tissue Type: Human Brain Cortex

TrkC Antibody Immunofluorescence validation (1:100 dilution) in Human Brain Cortex (Cat no:66380-1-Ig)