Napsin A Recombinant antibody, PBS Only

• 

  WB analysis using 86052-1-RR (same clone as 86052-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86052-1-RR (NAPSA antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86052-1-PBS in a different storage buffer formulation.

Napsin A Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Cat No. 86052-1-PBS

Clone No.242433D1

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

Synonyms

NAPSA, Asp 4, ASP4, Aspartyl protease 4, EC:3.4.23.-

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Product Information

86052-1-PBS targets Napsin A in applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Napsin A fusion protein Ag9721
• Full Name: napsin A aspartic peptidase
• Calculated Molecular Weight: 420 aa, 45 kDa
• Observed Molecular Weight: 40-45 kDa
• GenBank Accession Number: BC017842
• Gene Symbol: Napsin A
• Gene ID (NCBI): 9476
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: O96009
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Napsin is found in two isoforms, napsin A and B, with highly homologous nucleotide sequences (91.2%). Napsin A appears to be a functional proteinase, predominantly expressed in lung and kidney. Napsin B is transcribed exclusively in cells related to the immune system and lacks an in-frame stop codon and is believed to be a pseudogene.(PMID:12698189). Napsin A is superior to TTF-1 in distinguishing primary lung ACA from other carcinomas (except kidney), particularly primary lung small cell carcinoma, and primary thyroid carcinoma.(PMID:22288963).