NeutraControl EPO Monoclonal antibody

NeutraControl EPO Monoclonal Antibody for Non-Neutralization, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

Non-Neutralization, ELISA

Conjugate

Unconjugated

CloneNo.

1D3B1

Cat no : 69519-1-Ig

Synonyms

EP, EPO, Epoetin, erythropoietin, MVCD2



Product Information

69519-1-Ig targets EPO in Non-Neutralization, ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen human Humankine EPO protein HZ-1168
Full Name erythropoietin
Gene symbol EPO
Gene ID (NCBI) 2056
Conjugate Unconjugated
Form Lyophilized Powder
Purification Method Protein G purification
Storage Buffer Sterile PBS.
Endotoxin<0.1 EU/μg
ReconstitutionThis product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use.
Stability and StorageLyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.

Background Information

Erythropoietin (Epo) is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. Its effect is realized by binding erythropoietin receptor (EpoR) expressed on erythroid progenitor cells. EpoR, is a glycoprotein expressed on megakaryocytes, erythroid progenitors and endothelial cells. Epo also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types.

This antibody is a neutralizing control antibody for EPO, the immunogen is the same as Neutrakine 69019-1-Ig but could not neutralize human EPO.