OLIG2 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66513-1-Ig |CloneNo.: 1E8C5

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Freight/Packing

Con: 150 μg/150 μl

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Species specificity:
Human

Positive WB detected in:
rat brain tissue,human brain tissue, human cerebellum tissue

Positive IHC detected in:
human brain tissue,human gliomas tissue

Recommended dilution:
WB : 1:1000-1:6000
IHC : 1:350-1:1400

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
oligodendrocyte lineage transcription factor 2

Calculated molecular weight:
32 kDa

Observed molecular weight:
35-39 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
OLIG2

Synonyms
BHLHB1, bHLHe19, OLIG2, OLIGO2, PRKCBP2, RACK17
Background

OLIG2, also named as BHLHB1, BHLHE19, PRKCBP2 and RACK17, is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1, OLIG2 establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development. OLIG2 is widely expressed in subsets of glia cells and progenitors, and it is strongly induced at different sites by both acute and chronic injury, albeit with different mechanisms. OLIG2 acts as a repressor of neurogenesis in cells reacting to brain injury. It may represent an effective approach towards evoking neuronal repair from parenchymal precursors.(PMID:19390819 )


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