OTC Monoclonal antibody

OTC Monoclonal Antibody for IHC, WB, ELISA

Host / Isotype

Mouse / IgG2a


Human, mouse, rat, pig







Cat no : 67553-1-Ig


OCTD, ornithine carbamoyltransferase, Ornithine transcarbamylase, OTC, OTCase

Tested Applications

Positive WB detected inpig liver tissue, rat liver tissue, mouse liver tissue
Positive IHC detected inhuman liver cancer tissue, human liver tissue, rat colon tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

Western Blot (WB)WB : 1:5000-1:50000
Immunohistochemistry (IHC)IHC : 1:4000-1:16000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Product Information

67553-1-Ig targets OTC in WB, IHC, ELISA applications and shows reactivity with Human, mouse, rat, pig samples.

Tested Reactivity Human, mouse, rat, pig
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen OTC fusion protein Ag24186
Full Name ornithine carbamoyltransferase
Calculated molecular weight 354 aa, 40 kDa
Observed molecular weight 36 kDa
GenBank accession numberBC074745
Gene symbol OTC
Gene ID (NCBI) 5009
Conjugate Unconjugated
Form Liquid
Purification Method Protein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Ornithine transcarbamylase (OTC) is a liver and intestinal mucosa-located, intramitochondrial, rate-limiting enzyme in the urea cycle. It catalyzes the reaction that converts ornithine and carbamoyl phosphate into citrulline, which is the second step of the urea cycle, to detoxify the ammonia produced from amino acid catabolism.


Product Specific Protocols
WB protocol for OTC antibody 67553-1-IgDownload protocol
IHC protocol for OTC antibody 67553-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols