PAR3 Recombinant monoclonal antibody, PBS Only

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• PAR3 Recombinant monoclonal antibody, PBS Only (84593-1-PBS)

PAR3 Uni-rAb^® Recombinant Antibody for WB, IF/ICC, Indirect ELISA

Cat No. 84593-1-PBS Copied!

Clone No. 241780F7

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Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF/ICC, Indirect ELISA

Synonyms

F2RL2, 241780F7, Coagulation factor II receptor-like 2, PAR 3, PAR-3

• 

  WB analysis using 84593-1-RR (same clone as 84593-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84593-1-RR (PAR3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84593-1-PBS in a different storage buffer formulation.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  IF Staining of U2OS using 84593-1-RR (same clone as 84593-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed U2OS cells using PAR3 antibody (84593-1-RR, Clone: 241780F7 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84593-1-PBS in a different storage buffer formulation.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Product Information

84593-1-PBS targets PAR3 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: coagulation factor II (thrombin) receptor-like 2
• Calculated Molecular Weight: 374 aa, 43 kDa
• Observed Molecular Weight: 45 kDa
• GenBank Accession Number: BC093648
• Gene Symbol: PAR3
• Gene ID (NCBI): 2151
• RRID: AB_3672089
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: O00254
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

PAR3 is a crucial protein involved in the establishment and maintenance of cell polarity across various species. It plays a significant role in organizing cellular structures and functions, particularly in epithelial and neuronal cells. PAR3 has been implicated in various aspects of cancer biology. It can act as a tumor suppressor in epithelial cancers, and its expression or mutations have been associated with the progression and behavior of glioblastoma, pancreatic cancer, and other malignancies.