PAR3 Recombinant monoclonal antibody, PBS Only

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  WB analysis using 84593-1-RR (same clone as 84593-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84593-1-RR (PAR3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84593-1-PBS in a different storage buffer formulation.

PAR3 Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 84593-1-PBS

Clone No.241780F7

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

F2RL2, Proteinase-activated receptor 3, PAR-3, PAR 3, Coagulation factor II receptor-like 2

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Product Information

84593-1-PBS targets PAR3 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: coagulation factor II (thrombin) receptor-like 2
• Calculated Molecular Weight: 374 aa, 43 kDa
• Observed Molecular Weight: 45 kDa
• GenBank Accession Number: BC093648
• Gene Symbol: PAR3
• Gene ID (NCBI): 2151
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: O00254
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

PAR3 is a crucial protein involved in the establishment and maintenance of cell polarity across various species. It plays a significant role in organizing cellular structures and functions, particularly in epithelial and neuronal cells. PAR3 has been implicated in various aspects of cancer biology. It can act as a tumor suppressor in epithelial cancers, and its expression or mutations have been associated with the progression and behavior of glioblastoma, pancreatic cancer, and other malignancies.