CPB1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 12600-1-AP

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Freight/Packing

Con: 60 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse pancreas tissue, mouse pancreas tissue, rat pancreas tissue

Positive IHC detected in:
human pancreas cancer tissue, human kidney tissue, human pancreas tissue, human pancreas cancer tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
carboxypeptidase B1 (tissue)

Calculated molecular weight:
417aa,47 kDa

Observed molecular weight:
47 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CPB1

Synonyms
Carboxypeptidase B, carboxypeptidase B1 (tissue), CPB, CPB1, DKFZp779K1333, Pancreas specific protein, PASP, PCPB
Background

PASP(pancreas-specific protein) is also named as CPB1, CPB, PCPB and belongs to the peptidase M14 family. This protein modulates the plasminogen system both in the matrix and on the cell surface, thus leading to the inhibition of endothelial cell movement and tube formation. It is initially described as a pancreatic metallocarboxypeptidase and is a marker for acute pancreatitis(PMID:19717511). The deduced 416-amino acid preproenzyme has a 15-amino acid signal peptide and a 95-amino acid activation peptide.


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