PCDHA2 Polyclonal antibody

PCDHA2 Polyclonal Antibody for IP, WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IP,ELISA

Conjugate

Unconjugated

Cat no : 10127-2-AP

Synonyms

PCDH alpha 2, PCDH ALPHA2, PCDHA2, protocadherin alpha 2



Tested Applications

Positive WB detected inmouse brain tissue, Raji cells, human heart tissue, HeLa cells, human brain tissue, mouse cerebellum tissue, rat brain tissue, rat cerebellum tissue
Positive IP detected inHeLa cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
Sample-dependent, check data in validation data gallery

Product Information

10127-2-AP targets PCDHA2 in WB, IP,ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen PCDHA2 fusion protein Ag0173
Full Name protocadherin alpha 2
Calculated molecular weight 102 kDa
Observed molecular weight 102 kDa, 80 kDa
GenBank accession numberBC003126
Gene symbol PCDHA2
Gene ID (NCBI) 56146
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Protocadherins, which constitute the largest subgroup within the cadherin superfamily, are predominantly expressed in the nervous system and are probably involved in the regulation of neuronal recognition and connectivity (PMID: 17936607; 12231349; 17133224). The protocadherin subfamily can be further subdivided into three groups: the clustered protocadherins, comprising α-, β- and γ-protocadherins; δ-protocadherins; and others, many of which are solitary (PMID: 17133224). PCDHA2 (protocadherin alpha 2) is a single-pass type I membrane protein containing 6 cadherin domains. It may be involved in the establishment and maintenance of specific neuronal connections in the brain. Three isoforms produced by alternative splicing have been described (UniProt).

Protocols

Product Specific Protocols
WB protocol for PCDHA2 antibody 10127-2-APDownload protocol
IP protocol for PCDHA2 antibody 10127-2-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols