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PCDHGC3 Polyclonal antibody, PBS Only (10857-1-PBS)

Filter: AllIHCIF/ICC

IHC staining of human breast cancer using 10857-1-AP (same clone as 10857-1-PBS)
Immunohistochemical analysis of paraffin-embedded human breast cancer using 10857-1-AP (PCDHGC3 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 10857-1-PBS in a different storage buffer formulation.
IHC staining of mouse brain using 10857-1-AP (same clone as 10857-1-PBS)
Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 10857-1-AP (PCDHGC3 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10857-1-PBS in a different storage buffer formulation.
IHC staining of mouse brain using 10857-1-AP (same clone as 10857-1-PBS)
Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 10857-1-AP (PCDHGC3 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10857-1-PBS in a different storage buffer formulation.
IF Staining of SH-SY5Y using 10857-1-AP (same clone as 10857-1-PBS)
Immunofluorescent analysis of (-20°C Ethanol) fixed SH-SY5Y cells using PCDHGC3 antibody (10857-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 10857-1-PBS in a different storage buffer formulation.

PCDHGC3 Polyclonal antibody, PBS Only

Name: PCDHGC3 Polyclonal antibody, PBS Only
Brand: Proteintech
SKU: 10857-1-PBS

PCDHGC3 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA

Cat No. 10857-1-PBS

Review Product

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, IF/ICC, Indirect ELISA

Synonyms

PC-43, PCDH2, PCDH-gamma-C3, Protocadherin gamma-C3, Protocadherin-2

Formulation: PBS Only

PBS, Azide, Glycerol

Conjugate: Unconjugated

Size/Concentration:

-/ -

Freight/Packing: -

Quantity

- +

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Overview

Tested Applications
Product Information

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MSDS SDS

Product Information

10857-1-PBS targets PCDHGC3 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity	human, mouse
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	CatNo: Ag1243 Product name: Recombinant human PCDHGC3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 612-934 aa of BC019299 Sequence: GSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK Predict reactive species
Full Name	protocadherin gamma subfamily C, 3
Calculated Molecular Weight	150 kDa
GenBank Accession Number	BC019299
Gene Symbol	PCDHGC3
Gene ID (NCBI)	5098
RRID	AB_2159713
Conjugate	Unconjugated
Form	Liquid
Purification Method	Antigen affinity purification
UNIPROT ID	Q9UN70
Storage Buffer	PBS only, pH 7.3.
Storage Conditions	Store at -80°C.

Background Information

PCDHGC3, a member of the PCDHγ cluster, has been described in some studies as a tumor suppressor that promotes the apoptosis of tumor cells, as well as suppresses the Wnt- and mTOR-signaling pathways, which negatively affects the growth of various tumors such as Wilms tumors, breast cancer, or prostate cancer.