PDGFR alpha/CD140a Recombinant antibody, PBS Only

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  WB analysis using 84383-2-RR (same clone as 84383-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84383-2-RR (PDGFRA antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84383-2-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84383-2-RR

  Biolayer interferometry (BLl) kinetic assays of 84383-2-RR against Human PDGFR alpha/CD140a were performed. The affinity constant is 1.21 nM.

PDGFR alpha/CD140a Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Cat No. 84383-2-PBS

Clone No.241658G6

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Synonyms

PDGFRA, 241658G6, Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A

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Product Information

84383-2-PBS targets PDGFR alpha/CD140a in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant Protein
• Full Name: platelet-derived growth factor receptor, alpha polypeptide
• Calculated Molecular Weight: 123 kDa
• Observed Molecular Weight: 170-190 kDa
• GenBank Accession Number: BC015186
• Gene Symbol: PDGFR alpha
• Gene ID (NCBI): 5156
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P16234
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Platelet-derived growth factor receptor alpha (PDGFRA, also known as CD140a) is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. PDGFRA is implicated in the regulation of embryonic development, tumorigenesis, cell proliferation, survival, and chemotaxis. Mutations in the PDGFRA gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.