PEX11A Polyclonal antibody

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  WB analysis of mouse kidney using 15481-1-AP

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 15481-1-AP (PEX11A antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

PEX11A Polyclonal Antibody for WB, ELISA

Cat No. 15481-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Synonyms

HsPEX11p, Peroxin 11A, PEX11, PEX11 ALPHA, PEX11A, PMP28, Protein PEX11 homolog alpha

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Tested Applications

• Positive WB detected in: mouse kidney tissue

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

15481-1-AP targets PEX11A in WB, ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag7797

  Product name: Recombinant human PEX11A protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 1-247 aa of BC009697

  Sequence: MDAFTRFTNQTQGRDRLFRATQYTCMLLRYLLEPKAGKEKVVMKLKKLESSVSTGRKWFRLGNVVHAIQATEQSIHATDLVPRLCLTLANLNRVIYFICDTILWVRSVGLTSGINKEKWRTRAAHHYYYSLLLSLVRDLYEISLQMKRVTCDRAKKEKSASQDPLWFSVAEEETEWLQSFLLLLFRSLKQHPPLLLDTVKNLCDILNPLDQLGIYKSNPGIIGLGGLVSSIAGMITVAYPQMKLKTR

• Full Name: peroxisomal biogenesis factor 11 alpha
• Calculated Molecular Weight: 28 kDa
• Observed Molecular Weight: 28 kDa
• GenBank Accession Number: BC009697
• Gene Symbol: PEX11A
• Gene ID (NCBI): 8800
• RRID: AB_3085464
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: O75192
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Peroxisomes are ubiquitous organelles bound by a single membrane. Peroxisomal biogenesis factor 11 alpha (PEX11A) is one of PEX11 gene family members involved in peroxisome elongation. PEX11A is highly expressed in the kidney and liver (PMID: 25113963). PEX11A deficiency will impaire peroxisome elongation, leading to the reduction of functional peroxisome, eventually leading to the reduction of fatty acid oxidation capacity and the formation of steatosis (PMID: 23169785; PMID: 25113963)