PEX3 Recombinant monoclonal antibody, PBS Only

• 

  WB analysis using 86594-1-RR (same clone as 86594-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86594-1-RR (PEX3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86594-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 86594-1-RR (same clone as 86594-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86594-1-RR (PEX3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86594-1-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 86594-1-RR

  Biolayer interferometry (BLl) kinetic assays of 86594-1-RR against Human PEX3 were performed. The affinity constant is below 1 pM.

PEX3 Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 86594-1-PBS

Clone No.251383E9

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

Peroxin 3, Peroxin-3, PEX

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Product Information

86594-1-PBS targets PEX3 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Ag31516

  Product name: Recombinant human PEX3 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 37-140 aa of BC014551

  Sequence: IREIQEREAAEYIAQARRQYHFESNQRTCNMTVLSMLPTLREALMQQLNSESLTALLKNRPSNKLEIWEDLKIISFTRSTVAVYSTCMLVVLLRVQLNIIGGYI

• Full Name: peroxisomal biogenesis factor 3
• Calculated Molecular Weight: 42 kDa
• Observed Molecular Weight: 42 kDa
• GenBank Accession Number: BC014551
• Gene Symbol: PEX3
• Gene ID (NCBI): 8504
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P56589
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. Peroxin 3, also known as PEX3 (peroxisomal biogenesis factor 3) or TRG18, is a 373 amino acid multi-pass membrane protein that anchored in the peroxisomal membrane and essential for peroxisome biogenesis and integrity. Additionally, Peroxin 3 acts as a docking factor for Peroxin 19 and is required for the import of peroxisomal proteins. Defects in the gene encoding Peroxin 3 are the cause of peroxisome biogenesis disorder complementation group 12 (PBD-CG12) and Zellweger syndrome (ZwS), both of which arise from a failure of peroxisomal protein import.