PLEKHN1 Polyclonal antibody

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  WB analysis using 33028-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 33028-1-AP (PLEKHN1 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

PLEKHN1 Polyclonal Antibody for WB, ELISA

Cat No. 33028-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Synonyms

CLPABP

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Tested Applications

• Positive WB detected in: A431 cells, HT-29 cells, mouse brain tissue, mouse cerebellum tissue, rat brain tissue, rat cerebellum tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

33028-1-AP targets PLEKHN1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: PLEKHN1 fusion protein Ag38741
• Full Name: pleckstrin homology domain containing, family N member 1
• Calculated Molecular Weight: 663 aa, 72 kDa
• Observed Molecular Weight: 66-71 kDa
• GenBank Accession Number: BC101386
• Gene Symbol: PLEKHN1
• Gene ID (NCBI): 84069
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: Q494U1
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

PLEKHN1 (Pleckstrin Homology Domain Containing N1) is a protein-coding gene located on chromosome 1. It plays a crucial role in various cellular processes, including apoptosis and mRNA stability regulation. PLEKHN1 has been identified as a pro-apoptotic protein that enhances Bax-Bak hetero-oligomerization via interaction with Bid in colon cancer cells. (PMID: 29531808)