Product Information
22054-1-PBS targets POC5 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag17060 Product name: Recombinant human C5orf37 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 202-550 aa of BC101325 Sequence: RKDEVISSLSHAIGKQKEKIELMRTFFHWRIGHVRARQDVYEGKLADQYYQRTLLKKVWKVWRSVVQKQWKDVVERACQARAEEVCIQISNDYEAKVAMLSGALENAKAEIQRMQHEKEHFEDSMKKAFMRGVCALNLEAMTIFQNRNDAGIDSTNNKKEEYGPGVQGKEHSAHLDPSAPPMPLPVTSPLLPSPPAAVGGASATAVPSAASMTSTRAASASSVHVPVSALGAGSAATAASEEMYVPRVVTSAQQKAGRTITARITGRCDFASKNRISSSLAIMGVSPPMSSVVVEKHHPVTVQTIPQATAAKYPRTIHPESSTSASRSLGTRSAHTQSLTSVHSIKVVD Predict reactive species |
| Full Name | chromosome 5 open reading frame 37 |
| Calculated Molecular Weight | 575 aa, 63 kDa |
| Observed Molecular Weight | 60-65 kDa |
| GenBank Accession Number | BC101325 |
| Gene Symbol | C5orf37 |
| Gene ID (NCBI) | 134359 |
| RRID | AB_3742063 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8NA72 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
POC5 (POC5 Centriolar Protein) is a conserved protein essential for the assembly and structural integrity of the centriole, a core component of the centrosome and cilia. Localized to the distal portion of the centriole, it plays a critical role in centriole elongation, stabilization, and the maintenance of its characteristic nine-fold symmetric microtubule arrangement. By ensuring accurate centriole duplication, POC5 contributes to proper mitotic spindle formation and faithful chromosome segregation during cell division.
