Product Information
15019-1-PBS targets POMGNT1 in IP, Indirect ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag7029 Product name: Recombinant human POMGNT1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 313-660 aa of BC001471 Sequence: NYLYRMLRSLLSAQGVSPQMITVFIDGYYEEPMDVVALFGLRGIQHTPISIKNARVSQHYKASLTATFNLFPEAKFAVVLEEDLDIAVDFFSFLSQSIHLLEEDDSLYCISAWNDQGYEHTAEDPALLYRVETMPGLGWVLRRSLYKEELEPKWPTPEKLWDWDMWMRMPEQRRGRECIIPDVSRSYHFGIVGLNMNGYFHEAYFKKHKFNTVPGVQLRNVDSLKKEAYEVEVHRLLSEAEVLDHSKNPCEDSFLPDTEGHTYVAFIRMEKDDDFTTWTQLAKCLHIWDLDVRGNHRGLWRLFRKKNHFLVVGVPASPYSVKKPPSVTPIFLEPPPKEEGAPGAPEQT Predict reactive species |
| Full Name | protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase |
| Calculated Molecular Weight | 75 kDa |
| GenBank Accession Number | BC001471 |
| Gene Symbol | POMGNT1 |
| Gene ID (NCBI) | 55624 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8WZA1 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
POMGnT1 (Protein O-linked mannose β-1,2-N-acetylglucosaminyltransferase 1) catalyzes the formation of the N-acetylglucosamine β-1,2-Man linkage of O-mannosylglycan, which can increase the protein posttranslational mannosylation level. Defects in POMGNT1 affect neuronal migration and distribution, disrupt basement membranes, and misalign Cajal-Retzius cells (PMID: 36686576). POMGNT1 is mainly enriched in glutamatergic neurons. POMGnT1 is a 660-amino-acid Golgi glycosyltransferase and mainly enriched in glutamatergic neurons. (PMID: 11709191).
