Product Information
25736-1-PBS targets PRIC285 in IP, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag22719 Product name: Recombinant human PRIC285 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1733-2080 aa of BC150283 Sequence: DTRLQRGELFSREDLVWYKKVLWEARKFELDRHEVILCTCSCAASASLKILDVRQILVDEAGMATEPETLIPLVQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHEDAHMLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLVPAGQVRVCRRPTMPS Predict reactive species |
| Full Name | peroxisomal proliferator-activated receptor A interacting complex 285 |
| Calculated Molecular Weight | 2649 aa, 295 kDa |
| Observed Molecular Weight | 294 kDa |
| GenBank Accession Number | BC150283 |
| Gene Symbol | PRIC285 |
| Gene ID (NCBI) | 85441 |
| RRID | AB_3742156 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9BYK8 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
PRIC285, also known as HELZ2, is a member of the E3 ubiquitin ligase family, specifically the RING finger protein family. Its principal function is to serve as a nuclear transcriptional co-regulator within the peroxisome proliferator-activated receptor (PPAR) signaling pathway, thereby influencing lipid metabolism and energy homeostasis through the regulation of gene expression.
