AMPK gamma 1 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 10290-1-AP

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Freight/Packing

Con: 43 μg/150 μl

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Species specificity:
human

Positive WB detected in:
K-562 cells, HeLa cells, Jurkat cells

Positive IP detected in:
K-562 cells,

Positive IHC detected in:
human testis tissue, human skeletal muscle tissue, human testis tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
protein kinase, AMP-activated, gamma 1 non-catalytic subunit

Calculated molecular weight:
38 kDa

Observed molecular weight:
35-38 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PRKAG1

Synonyms
AMPK gamma1, AMPK subunit gamma 1, AMPKG, PRKAG1
Background

Protein kinase, AMP-activated, gamma 1 non-catalytic subunit (PRKAG1, synonyms: AMPKG, MGC8666) is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an catalytic subunit, and non-catalytic and subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and -hydroxy-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK.


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