AMPK gamma2 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 12568-1-AP

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Freight/Packing

Con: 26 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse heart tissue, HEK-293 cells, HeLa cells, mouse eye tissue, PC-3 cells

Positive IHC detected in:
human heart tissue, human heart tissue, human ovary tumor tissue, human placenta tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:50-1:500
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
protein kinase, AMP-activated, gamma 2 non-catalytic subunit

Calculated molecular weight:
569aa,63 kDa

Observed molecular weight:
63 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PRKAG2

Synonyms
AAKG, AAKG2, AMPK gamma2, AMPK subunit gamma 2, CMH6, H91620p, PRKAG2, WPWS
Background

AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. AMPK gamma2 is a member of the AMPK gamma subunit family. Mutations in this gene have been associated with Wolff-Parkinson-White syndrome, familial hypertrophic cardiomyopathy, and glycogen storage disease of the heart.


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