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- KD/KO Validated
PROX1 Antibody
PROX1 Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat and More (1)
Applications
WB, IHC, IF, CoIP, ChIP, ELISA
Conjugate
Unconjugated
Cat no : 51043-1-AP
Synonyms
prospero homeobox 1, Prospero homeobox protein 1, PROX 1, PROX1
Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| Sample-dependent, check data in validation data gallery | |
Published Applications
| KD/KO | See 3 publications below |
| WB | See 5 publications below |
| IHC | See 2 publications below |
| IF | See 2 publications below |
| CoIP | See 2 publications below |
| ChIP | See 2 publications below |
Product Information
51043-1-AP targets PROX1 in WB, IHC, IF, CoIP, ChIP, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | hamster, human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | PROX1 fusion protein Ag0457 |
| Full Name | prospero homeobox 1 |
| Calculated molecular weight | 737aa,83 kDa |
| Observed molecular weight | 90 kDa |
| GenBank accession number | BC024201 |
| Gene symbol | PROX1 |
| Gene ID (NCBI) | 5629 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Aliquoting is unnecessary for -20oC storage. |
Background Information
PROX1, Prospero homeobox protein 1, belongs to the Prospero homeobox family and contain a Prospero-type homeobox DNA-binding domain. PROX1 plays a fundamental role in early development of CNS and regulated the expression of gene and development of postmitotic undifferentiated young neuron. Also PROX1 is a specific and required regulator of the development of the lymphatic system. This is a rabbit polyclonal antibody raised against part of C-terminal chain of human PROX1.
Publications
| Species | Application | Title |
|---|---|---|
Int J Biomed Sci Prox1 Facilitates Transfected CHO Cell Proliferation through Activation of the AKT Signaling Pathway. | ||
Anticancer Res Proliferation of Small Cell Lung Cancer Cell Line Reduced by Knocking-down PROX1 via shRNA in Lentivirus. | ||
Biol Pharm Bull Establishment and characterization of a human lymphatic endothelial cell line. | ||
PLoS One Impact of an Altered PROX1 Expression on Clinicopathology, Prognosis and Progression in Renal Cell Carcinoma. | ||
Am J Pathol Lymphotoxins Promote the Progression of Human Lymphatic Malformation by Enhancing Lymphatic Endothelial Cell Proliferation. |
