• Featured Product
  • KD/KO Validated

PROX1 Polyclonal antibody

PROX1 Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat and More (1)

Applications

WB, IHC, IF, CoIP, ChIP,ELISA

Conjugate

Unconjugated

Cat no : 51043-1-AP

Synonyms

prospero homeobox 1, Prospero homeobox protein 1, PROX 1, PROX1



Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

51043-1-AP targets PROX1 in WB, IHC, IF, CoIP, ChIP,ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, hamster
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen PROX1 fusion protein Ag0457
Full Name prospero homeobox 1
Calculated Molecular Weight 737 aa, 83 kDa
Observed Molecular Weight 90 kDa
GenBank Accession NumberBC024201
Gene Symbol PROX1
Gene ID (NCBI) 5629
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

PROX1, Prospero homeobox protein 1, belongs to the Prospero homeobox family and contain a Prospero-type homeobox DNA-binding domain. PROX1 plays a fundamental role in early development of CNS and regulated the expression of gene and development of postmitotic undifferentiated young neuron. Also PROX1 is a specific and required regulator of the development of the lymphatic system. This is a rabbit polyclonal antibody raised against part of C-terminal chain of human PROX1.

Publications

SpeciesApplicationTitle
human,mouseWB,CoIP,ChIP

Genes Dev

The homeobox protein Prox1 is a negative modulator of ERR{alpha}/PGC-1{alpha} bioenergetic functions.

Authors - Charest-Marcotte Alexis A
  • KD Validated
mouseCoIP,chIP

Nat Commun

An HDAC3-PROX1 corepressor module acts on HNF4α to control hepatic triglycerides.

Authors - Sean M Armour
humanWB

PLoS Genet

Genomic convergence among ERRα, PROX1, and BMAL1 in the control of metabolic clock outputs.

Authors - Dufour Catherine R CR
  • KD Validated
humanWB

Nucleic Acids Res

Prospero-related homeobox 1 (Prox1) functions as a novel modulator of retinoic acid-related orphan receptors α- and γ-mediated transactivation.

Authors - Takeda Yukimasa Y
  • KD Validated
humanIHC,IF

Am J Pathol

Lymphotoxins Promote the Progression of Human Lymphatic Malformation by Enhancing Lymphatic Endothelial Cell Proliferation.

Authors - Jie-Gang Yang
humanIHC

PLoS One

Impact of an Altered PROX1 Expression on Clinicopathology, Prognosis and Progression in Renal Cell Carcinoma.

Authors - Tao Lv