PRPH2 Recombinant monoclonal antibody, PBS Only

• 

  WB analysis using 85043-2-RR (same clone as 85043-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85043-2-RR (PRPH2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85043-2-PBS in a different storage buffer formulation.

• 

  WB analysis using 85043-2-RR (same clone as 85043-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85043-2-RR (PRPH2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85043-2-PBS in a different storage buffer formulation.

PRPH2 Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 85043-2-PBS

Clone No.242170C1

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

242170C1, AOFMD, AVMD, Peripherin 2, Peripherin2

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Product Information

85043-2-PBS targets PRPH2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Ag12555

  Product name: Recombinant human PRPH2 protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 124-346 aa of BC074720

  Sequence: GSLENTLGQGLKNGMKYYRDTDTPGRCFMKKTIDMLQIEFKCCGNNGFRDWFEIQWISNRYLDFSSKEVKDRIKSNVDGRYLVDGVPFSCCNPSSPRPCIQYQITNNSAHYSYDHQTEELNLWVRGCRAALLSYYSSLMNSMGVVTLLIWLFEVTITIGLRYLQTSLDGVSNPEESESESEGWLLEKSVPETWKAFLESVKKLGKGNQVEAEGAGAGQAPEAG

• Full Name: peripherin 2 (retinal degeneration, slow)
• Calculated Molecular Weight: 346 aa, 39 kDa
• Observed Molecular Weight: 35-39 kDa
• GenBank Accession Number: BC074720
• Gene Symbol: PRPH2
• Gene ID (NCBI): 5961
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: P23942
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Peripherin-2 (PRPH2), also known as retinal degeneration slow protein (RDS), is a photoreceptor-specific tetraspanin protein implicated in outer segment disk morphogenesis. It may function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in maintaining the curvature of the rim. Mutations in peripherin-2 are responsible for various retinal degenerative diseases including autosomal dominant retinitis pigmentosa (ADRP).