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PSD2 Polyclonal antibody

PSD2 Polyclonal Antibody for WB, ELISA

Cat No. 17404-1-AP

Publications (2)

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Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF, ELISA

Synonyms

EFA6C, Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 C, Exchange factor for ARF6 C, PH and SEC7 domain-containing protein 2, Pleckstrin homology and SEC7 domain-containing protein 2

Formulation: PBS, Azide, Glycerol

Conjugate: Unconjugated

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Filter: AllWB

WB analysis of mouse brain using 17404-1-AP
mouse brain tissue were subjected to SDS PAGE followed by western blot with 17404-1-AP (PSD2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
WB analysis of mouse brain using 17404-1-AP
mouse brain tissue were subjected to SDS PAGE followed by western blot with 17404-1-AP (PSD2 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Overview

Tested Applications
Product Information
Publications (2)

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MSDS SDS

Tested Applications

Positive WB detected in

mouse brain tissue

Recommended dilution

Application	Dilution
Western Blot (WB)	WB : 1:500-1:3000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

17404-1-AP targets PSD2 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity	human, mouse, rat
Cited Reactivity	mouse
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	CatNo: Ag11386 Product name: Recombinant human PSD2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 418-771 aa of BC038233 Sequence: TDLHGHNIGKKMSCQQFIANLDQLNDGQDFAKDLLKTLYNSIKNEKLEWAIDEDELRKSLSELVDDKFGTGTKKVTRILDGGNPFLDVPQALSATTYKHGVLTRKTHADMDGKRTPRGRRGWKKFYAVLKGTILYLQKDEYRPDKALSEGDLKNAIRVHHALATRASDYSKKSNVLKLKTADWRVFLFQAPSKEEMLSWILRINLVAAIFSAPAFPAAVSSMKKFCRPLLPSCTTRLCQEEQLRSHENKLRQLTAELAEHRCHPVERGIKSKEAEEYRLKEHYLTFEKSRYETYIHLLAMKIKVGSDDLERIEARLATLEGDDPSLRKTHSSPALSQGHVTGSKTTKDATGPDT Predict reactive species
Full Name	pleckstrin and Sec7 domain containing 2
Calculated Molecular Weight	771 aa, 85 kDa
Observed Molecular Weight	85-95 kDa
GenBank Accession Number	BC038233
Gene Symbol	PSD2
Gene ID (NCBI)	84249
RRID	AB_2172759
Conjugate	Unconjugated
Form	Liquid
Purification Method	Antigen affinity purification
UNIPROT ID	Q9BQI7
Storage Buffer	PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions	Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Publications

What published studies show

The PSD2 polyclonal antibody (Cat# 17404-1-AP) has 2 citations. They appear in Frontiers in Synaptic Neuroscience (2018) and PLoS One (2019). Both studies focus on neuroscience, specifically synaptic biology and cerebellar function. The first examines proteomic analysis of dendritic filopodia-rich fractions, while the second investigates EFA6C/Psd2's role in Purkinje cell synaptic density and cerebellar motor function in knockout mice.

Species	Application	Title
mouse	IF	Front Synaptic Neurosci Proteomic Analysis of Dendritic Filopodia-Rich Fraction Isolated by Telencephalin and Vitronectin Interaction. Authors - Yutaka Furutani View Article
mouse	WB,IHC	PLoS One Mice lacking EFA6C/Psd2, a guanine nucleotide exchange factor for Arf6, exhibit lower Purkinje cell synaptic density but normal cerebellar motor functions. Authors - Shintaro Saegusa KO Validated View Article