Product Information
84934-1-PBS targets PSMC3IP in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | PSMC3IP fusion protein Ag1883 Predict reactive species |
Full Name | PSMC3 interacting protein |
Calculated Molecular Weight | 25 kDa |
Observed Molecular Weight | 24-29 kDa |
GenBank Accession Number | BC008792 |
Gene Symbol | PSMC3IP |
Gene ID (NCBI) | 29893 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q9P2W1 |
Storage Buffer | PBS only, pH 7.3. |
Storage Conditions | Store at -80°C. |
Background Information
PSMC3IP, also called HOP2, encodes a protein that functions in meiotic recombination. It is a subunit of the PSMC3IP/MND1 complex, which interacts with PSMC3/TBP1 to stimulate DMC1- and RAD51-mediated strand exchange during meiosis. The protein encoded by this gene can also co-activate ligand-driven transcription mediated by estrogen, androgen, glucocorticoid, progesterone, and thyroid nuclear receptors. Mutations in this gene cause XX female gonadal dysgenesis.