PTGDS Polyclonal antibody

PTGDS Polyclonal Antibody for IHC, WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC,ELISA

Conjugate

Unconjugated

Cat no : 10754-2-AP

Synonyms

Beta trace protein, Cerebrin 28, LPGDS, PDS, PGD2, PGD2 synthase, PGDS, PGDS2, Prostaglandin D2 synthase, Prostaglandin H2 D isomerase, PTGDS



Tested Applications

Positive WB detected inHeLa cells, human colon tissue, human heart tissue, human kidney tissue, PC-3 cells
Positive IHC detected inhuman lung cancer tissue, mouse brain tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:3000
Immunohistochemistry (IHC)IHC : 1:100-1:500
Sample-dependent, check data in validation data gallery

Product Information

10754-2-AP targets PTGDS in WB, IHC,ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen PTGDS fusion protein Ag1163
Full Name prostaglandin D2 synthase 21kDa (brain)
Calculated molecular weight 21 kDa
Observed molecular weight 28 kDa
GenBank accession numberBC005939
Gene symbol PTGDS
Gene ID (NCBI) 5730
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

PGDS(Prostaglandin-H2 D-isomerase) is also named as PTGDS, PDS, PGDS2. It catalyzes the conversion of PGH2 to PGD2, and is a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. It has two N-glycosylation recognition sites.

Protocols

Product Specific Protocols
WB protocol for PTGDS antibody 10754-2-APDownload protocol
IHC protocol for PTGDS antibody 10754-2-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanIHC

Cancer Manag Res

Decreased PTGDS Expression Predicting Poor Survival of Endometrial Cancer by Integrating Weighted Gene Co-Expression Network Analysis and Immunohistochemical Validation.

Authors - Ruoyao Zou
humanWB

Cell Cycle

MicroRNA-138 improves LPS-induced trophoblast dysfunction through targeting RELA and NF-κB signaling.

Authors - Ailan Yin
humanWB

Med Sci Monit

Proteome analysis of human cerebrospinal fluid as a diagnostic biomarker in patients with meningioma.

Authors - Kim Jae Ho JH