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PTGR2 Polyclonal antibody

PTGR2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

15-oxoprostaglandin 13-reductase, EC:1.3.1.48, PGR2, PRG 2, PRG-2

Formulation:  PBS, Azide, Glycerol
PBS, Azide, Glycerol
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 
SKU: 

-/ -

Freight/Packing: -

Quantity

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Tested Applications

Positive WB detected inmouse kidney tissue, BxPC-3 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

14164-1-AP targets PTGR2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag5352

Product name: Recombinant human PTGR2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-351 aa of BC059364

Sequence: MIVQRVVLNSRPGKNGNPVAENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDTGTDYITPWQLSQVVDGGGIGIIEESKHTNLTKGDFVTSFYWPWQTKVILDGNSLEKVDPQLVDGHLSYFLGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCILLTSELGFDAAINYKKDNVAEQLRESCPAGVDVYFDNVGGNISDTVISQMNENSHIILCGQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYKDKFEPGILQLSQWFKEGKLKIKETVINGLENMGAAFQSMMTGGNIGKQIVCISEEISL

Predict reactive species
Full Name prostaglandin reductase 2
Calculated Molecular Weight 351 aa, 39 kDa
Observed Molecular Weight 38.5 kDa
GenBank Accession NumberBC059364
Gene Symbol PTGR2
Gene ID (NCBI) 145482
RRIDAB_2173217
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8N8N7
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Protocols

Product Specific Protocols
WB protocol for PTGR2 antibody 14164-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

What published studies show

The PTGR2 Polyclonal antibody (catalog number 14164-1-AP) has 4 total citations. These appear in Cell Metabolism, Biochemical Pharmacology, Scientific Reports, and Phytotherapy Research. The associated research fields include m6A mRNA methylation and insulin sensitivity, lung ischemia-reperfusion injury, sunitinib resistance in renal cell carcinoma, and liver fibrosis involving bile acid and arachidonic acid metabolism.

SpeciesApplicationTitle
mouse,humanWB

Cell Metab

m6A mRNA methylation in brown fat regulates systemic insulin sensitivity via an inter-organ prostaglandin signaling axis independent of UCP1

Authors - Ling Xiao
mouseWB

Biochem Pharmacol

The tryptophan metabolite indole 3-propionic acid alleviates lung ischemia-reperfusion injury via prostaglandin reductase 2 in male mice.

Authors - Kai Guo
humanWB

Sci Rep

Genome-wide CRISPR/Cas9 screening identifies PTGR2 as a potential therapeutic target for sunitinib resistance in clear cell renal cell carcinoma

Authors - Wei Chang

Phytother Res

Ajugol Improves Liver Fibrosis by Modulating Bile Acid and Arachidonic Acid Metabolism in Mice.

Authors - Xia Wei
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