PUM1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 26256-1-AP

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Freight/Packing

Con: 46 μg/150 μl

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Species specificity:
human

Positive IP detected in:
MCF-7 cells

Positive IF detected in:
MCF-7 cells

Recommended dilution:
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
pumilio homolog 1 (Drosophila)

Calculated molecular weight:
1186aa,126 kDa

Observed molecular weight:
130-140 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PUM1

Synonyms
HSPUM, KIAA0099, PUM1, PUMH, PUMH1, Pumilio 1, Pumilio homolog 1, pumilio homolog 1 (Drosophila), PUML1
Background

PUM1, also named as Pumilio homolog 1, is a 1186 amino acid protein, which is expressed in brain, heart, kidney, muscle, intestine and stomach. PUM1 as sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3'-UTR of mRNA targets. PUM1 binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5'-UGUANAUA-3', that is related to the Nanos Response Element (NRE). The calculated molecular weight of PUM1 is 126 kDa, but the modified PUM1 is about 130-140 kDa.


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