PYROXD1 Recombinant antibody, PBS Only

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  WB analysis of HeLa using 84289-7-RR (same clone as 84289-7-PBS)

  WB result of PYROXD1 antibody (84289-7-RR; 1:3000; incubated at room temperature for 1.5 hours) with sh-Control and sh-PYROXD1 transfected HeLa cells. This data was developed using the same antibody clone with 84289-7-PBS in a different storage buffer formulation.

• 

  WB analysis using 84289-7-RR (same clone as 84289-7-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84289-7-RR (PYROXD1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84289-7-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84289-7-RR

  Biolayer interferometry (BLl) kinetic assays of 84289-7-RR against Human PYROXD1 were performed. The affinity constant is below 1 pM.

• Featured Product
• KD/KO Validated

PYROXD1 Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Cat No. 84289-7-PBS

Clone No.241639D7

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

241639D7, pyridine nucleotide disulphide oxidoreductase domain 1

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Product Information

84289-7-PBS targets PYROXD1 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: PYROXD1 fusion protein Ag34768
• Full Name: pyridine nucleotide-disulphide oxidoreductase domain 1
• Observed Molecular Weight: 55~60 kDa
• GenBank Accession Number: BC021662
• Gene Symbol: PYROXD1
• Gene ID (NCBI): 79912
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: Q8WU10
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

pyridine nucleotide-disulfide oxidoreductase domain 1 (PYROXD1) is a putative oxidoreductase that co-evolved with the tRNA-LC and is essential for its activity in cells and in vivo. PYROXD1 oxidizes NAD(P)H to NAD(P)+ with tightly controlled kinetics, reducing one molecule of O2 into H2O2 per turnover. PYROXD1 is expressed across a range of tissue types in humans, including skeletal muscle, and is conserved across many species.