Phospho-MEK6 (Ser207) Recombinant antibody, PBS Only

Phospho-MEK6 (Ser207) Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 80064-2-PBS
Clone No.250293G8

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

MKK6 (Ser207), Phospho-MEK6, Phospho-MEK6(Ser207), Phospho-MKK3 (Ser189), Phospho-MKK3 (Ser189)/MKK6 (Ser207)

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

80064-2-PBS targets Phospho-MEK6 (Ser207) in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Peptide Predict reactive species
Full Name mitogen-activated protein kinase kinase 6
Calculated Molecular Weight 334 aa, 37 kDa
Observed Molecular Weight38 kDa, 40kDa
GenBank Accession NumberBC012009
Gene Symbol MEK6
Gene ID (NCBI) 5608
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP52564
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

MAPKK6 (Dual specificity mitogen activated protein kinase kinase 6), also known as MAP2K6 / MEK6 / MKK6, is a member of MAPKK protein kinase family. MKK6 plays an important role in intracellular signaling pathways leading toward activation of the p38 MAP kinase. MEK6 phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. Phosphorylation of Ser207 and Thr211 by MAP3Ks is critical for MEK6 activation, and acetylation of these resides by VopA blocks MEK6 activity(PMID: 26648936). The antibody also recognizes the ser218 phosphorylation site of MEK3.

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