RAI1 Polyclonal antibody, PBS Only

• Home
• Products
• Primary Antibodies
• RAI1 Polyclonal antibody, PBS Only (17084-1-PBS)

• 

  WB analysis of HeLa using 17084-1-AP (same clone as 17084-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 17084-1-AP (RAI1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17084-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HeLa using 17084-1-AP (same clone as 17084-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 17084-1-AP (RAI1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17084-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human stomach cancer using 17084-1-AP (same clone as 17084-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 17084-1-AP (RAI1 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17084-1-PBS in a different storage buffer formulation.

RAI1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 17084-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Synonyms

KIAA1820, retinoic acid induced 1, Retinoic acid-induced protein 1, SMCR, SMS

---

Product Information

17084-1-PBS targets RAI1 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag9046

  Product name: Recombinant human RAI1 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-350 aa of BC021209

  Sequence: MQSFRERCGFHGKQQNYQQTSQETSRLENYRQPSQAGLSCDRQRLLAKDYYNPQPYPSYEGGAGTPSGTAAAVAADKYHRGSKALPTQQGLQGRPAFPGYGVQDSSPYPGRYAGEESLQAWGAPQPPPPQPQPLPAGVAKYDENLMKKTAVPPSRQYAEQGAQVPFRTHSLHVQQPPPPQQPLAYPKLQRQKLQNDIASPLPFPQGTHFPQHSQSFPTSSTYSSSVQGGGQGAHSYKSCTAPTAQPHDRPLTASSSLAPGQRVQNLHAYQSGRLSYDQQQQQQQQQQQQQQALQSRHHAQETLHYQNLAKYQHYGQQGQGYCQPDAAVRTPEQYYQTFSPSSSHSPARSV

• Full Name: retinoic acid induced 1
• Calculated Molecular Weight: 1906aa,203 kDa; 966aa,104 kDa
• Observed Molecular Weight: 250-260 kDa
• GenBank Accession Number: BC021209
• Gene Symbol: RAI1
• Gene ID (NCBI): 10743
• RRID: AB_2284824
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q7Z5J4
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

The RAI1 (Retinoic Acid Induced 1) gene is located on the short arm of chromosome 17. The RAI1 protein it encodes is a crucial transcriptional regulator, playing a central role in processes such as neurodevelopment, sleep regulation, circadian rhythms, and energy metabolism. This protein contains a chromatin domain that binds to specific DNA sequences and recruits other transcriptional co-factors to activate or repress the expression of downstream target genes. The RAI1 gene is extremely sensitive to haploinsufficiency, and its dysfunction is closely linked to several severe neurodevelopmental disorders. For instance, RAI1 haploinsufficiency causes Smith-Magenis syndrome, while duplication of the RAI1 gene is associated with Potocki-Lupski syndrome. Consequently, the RAI1 protein is a key molecule for understanding brain function and behavioral regulation, and a major focus of research for related genetic syndromes.