RANK/TNFRSF11A Polyclonal antibody, PBS Only

• Home
• Products
• Primary Antibodies
• RANK/TNFRSF11A Polyclonal antibody, PBS Only (55293-1-PBS)

• 

  WB analysis using 55293-1-AP (same clone as 55293-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 55293-1-AP (RANK antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55293-1-PBS in a different storage buffer formulation.

RANK/TNFRSF11A Polyclonal Antibody for WB, Indirect ELISA

Cat No. 55293-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

TNFRSF11A, TNR11, Receptor activator of NF-KB, Receptor activator of NF KB, RANK

---

Product Information

55293-1-PBS targets RANK/TNFRSF11A in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: tumor necrosis factor receptor superfamily, member 11a, NFKB activator
• Calculated Molecular Weight: 66 kDa
• Observed Molecular Weight: 80-90 kDa
• GenBank Accession Number: NM_003839
• Gene Symbol: TNFRSF11A
• Gene ID (NCBI): 8792
• RRID: AB_3670246
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9Y6Q6
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Tumor necrosis factor receptor superfamily member 11A (TNFRSF11A, also known as RANK, CD265, and ODFR) is the signaling receptor essential for osteoclast differentiation factor-mediated osteoclastogenesis and is involved in the regulation of interactions between T-cells and dendritic cells (PMID: 9878548). The RANK/RANKL/OPG system is a key regulator in bone resorption, and its dysregulation can lead to pathological bone loss (PMID: 37893470).