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  • KD/KO Validated

RBM10 Polyclonal antibody

RBM10 Polyclonal Antibody for IP, WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IP,ELISA

Conjugate

Unconjugated

Cat no : 14423-1-AP

Synonyms

DXS8237E, GPATC9, GPATCH9, KIAA0122, RBM10, RNA binding motif protein 10, RNA binding protein 10, RNA binding protein S1 1, S1 1, ZRANB5



Tested Applications

Positive WB detected inhuman brain tissue
Positive IP detected inmouse brain tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
Sample-dependent, check data in validation data gallery

Product Information

14423-1-AP targets RBM10 in WB, IP,ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen RBM10 fusion protein Ag5788
Full Name RNA binding motif protein 10
Calculated molecular weight 104 kDa
Observed molecular weight 115 kDa
GenBank accession numberBC024153
Gene symbol RBM10
Gene ID (NCBI) 8241
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

RBM10, also named as RNA-binding protein 10, is a 930 amino acid protein, which is in the extranucleolar nucleoplasm constitutes hundreds of nuclear domains, which dynamically change their structures in a reversible manner. RBM10 may be involved in post-transcriptional processing, most probably in mRNA splicing. RBM10 has some isoforms with MV 130 and 115 kDa (PMID: 25889998 and PMID: 18315527) .

Protocols

Product Specific Protocols
WB protocol for RBM10 antibody 14423-1-APDownload protocol
IP protocol for RBM10 antibody 14423-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

J Cell Mol Med

RBM10 inhibits cell proliferation of lung adenocarcinoma via RAP1/AKT/CREB signalling pathway.

Authors - Xin Jin
humanWB

BMC Mol Biol

Splicing arrays reveal novel RBM10 targets, including SMN2 pre-mRNA.

Authors - Leslie C Sutherland
  • KD Validated
humanWB

Oncogene

RNA-binding motif protein 10 induces apoptosis and suppresses proliferation by activating p53.

Authors - Ji Hoon Jung
  • KD Validated