RGS2 Polyclonal antibody

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• RGS2 Polyclonal antibody (10678-1-AP)

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• KD/KO Validated

RGS2 Polyclonal Antibody for WB, IHC, ELISA

Cat No. 10678-1-AP

Publications(11)

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF, IP, ELISA

Synonyms

G0S8, Cell growth inhibiting gene 31 protein, Cell growth-inhibiting gene 31 protein, G0/G1 switch regulatory protein 8, GIG31

• 

  WB analysis of fetal human brain using 10678-1-AP

  fetal human brain tissue were subjected to SDS PAGE followed by western blot with 10678-1-AP (RGS2 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  WB analysis of human brain using 10678-1-AP

  human brain tissue were subjected to SDS PAGE followed by western blot with 10678-1-AP (RGS2 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  IHC staining of human pancreas cancer using 10678-1-AP

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 10678-1-AP (RGS2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  IHC staining of mouse bladder using 10678-1-AP

  Immunohistochemical analysis of paraffin-embedded mouse bladder tissue slide using 10678-1-AP (RGS2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  IHC staining of mouse bladder using 10678-1-AP

  Immunohistochemical analysis of paraffin-embedded mouse bladder tissue slide using 10678-1-AP (RGS2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  IHC staining of mouse pancreas using 10678-1-AP

  Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue slide using 10678-1-AP (RGS2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  IHC staining of rat bladder using 10678-1-AP

  Immunohistochemical analysis of paraffin-embedded rat bladder tissue slide using 10678-1-AP (RGS2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  IHC staining of rat pancreas using 10678-1-AP

  Immunohistochemical analysis of paraffin-embedded rat pancreas tissue slide using 10678-1-AP (RGS2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  IHC staining of rat adrenal gland using 10678-1-AP

  Immunohistochemical analysis of paraffin-embedded rat adrenal gland tissue slide using 10678-1-AP (RGS2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Tested Applications

• Positive WB detected in: fetal human brain tissue, human brain tissue
• Positive IHC detected in: human pancreas cancer tissue, mouse bladder tissue, mouse pancreas tissue, rat adrenal gland tissue, rat bladder tissue, rat pancreas tissue; Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000
• Immunohistochemistry (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

10678-1-AP targets RGS2 in WB, IHC, IF, IP, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Cited Reactivity: human, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag1066

  Product name: Recombinant human RGS2 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-211 aa of BC007049

  Sequence: MQSAMFLAVQHDCRPMDKSAGSGHKSEEKREKMKRTLLKDWKTRLSYFLQNSSTPGKPKTGKKSKQQAFIKPSPEEAQLWSEAFDELLASKYGLAAFRAFLKSEFCEENIEFWLACEDFKKTKSPQKLSSKARKIYTDFIEKEAPKEINIDFQTKTLIAQNIQEATSGCFTTAQKRVYSLMENNSYPRFLESEFYQDLCKKPQITTEPHAT

• Full Name: regulator of G-protein signaling 2, 24kDa
• Calculated Molecular Weight: 24 kDa
• Observed Molecular Weight: 24-30 kDa
• GenBank Accession Number: BC007049
• Gene Symbol: RGS2
• Gene ID (NCBI): 5997
• RRID: AB_2284998
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P41220
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Publications

What published studies show

Automatically generated from the publication citations by Able AI.

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
human	WB	J Clin Invest; RGS2-mediated translational control mediates cancer cell dormancy and tumor relapse.; Authors - Jaebeom Cho ; KD Validated
human	WB	Basic Res Cardiol; Novel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2.; Authors - Klaiber Michael M
human	WB,IF	J Cell Physiol; Novel role of Giα2 in cell migration: Downstream of PI3-kinase-AKT and Rac1 in prostate cancer cells.; Authors - Silvia Caggia ; KD Validated
human	WB	Respir Res; Upregulation of RGS2: a new mechanism for pirfenidone amelioration of pulmonary fibrosis.; Authors - Yan Xie
human	WB	Virology; Transcriptomic analysis reveals crucial regulatory roles of immediate-early response genes and related signaling pathways in coronavirus infectious bronchitis virus infection; Authors - Li Xia Yuan
human	IF	Biomaterials; Modeling calcific aortic valve disease with engineered human valve tissues identifies SAMHD1 as a therapeutic target.; Authors - Xiangfu Meng